Amygdala, hippocampal and corpus callosum size following severe early institutional deprivation: the English and Romanian Adoptees study pilot
An MRI pilot compared 14 adolescent adoptees exposed to Romanian institutional deprivation with 11 non-adopted UK controls. The exposed group had smaller total grey and white matter volumes. After adjustment for overall brain volume, amygdala volumes differed, while hippocampal volume and corpus callosum area did not.
Limitations: Very small cross-sectional pilot; controls differed in both adoption status and institutional experience. Findings require replication. Extreme early institutional deprivation; results do not represent adoptees generally. Participants overlap with other ERA publications.
- Research type
- Cross-sectional neuroimaging study
- Source reviewed
- Abstract
- Peer reviewed
- Yes
- Age group
- Adolescents
Study context and review
Age group as recorded: Adolescents
Adoption context: Intercountry adoption after Romanian institutional care; UK comparison groups
Programme: English and Romanian Adoptees Study
Institutional context: No relationship identified in the material checked
No adoption-sector organisational relationship identified in indexed metadata reviewed. Affiliations, funding and conflicts have not been comprehensively audited; this does not confirm institutional independence.
Bibliographic screening. Bibliographic relationships are not a bias or safety rating.
Topics: brain structure, neurodevelopment
Review scope: Source checked: Abstract. This does not imply full-text or independent human verification.
Country as recorded: United Kingdom; Romania (origin)
- Funding
- Not yet checked for this entry
- Commissioner
- Not yet checked for this entry
- Funder role
- Not yet checked for this entry
- Declared conflicts
- Not yet checked for this entry
- Recruitment
- Not yet checked for this entry
- Adoptee involvement
- Not yet checked for this entry
Entry: study_b88de7c8cf136f7c