Early childhood deprivation is associated with alterations in adult brain structure despite subsequent environmental enrichment
MRI data from Romanian adoptees with severe early deprivation were compared with non-deprived UK adoptees. The deprived group had smaller total brain volume on average and regional structural differences, with duration of deprivation associated with brain volume.
Limitations: Small, unusual cohort; should not be generalised to adoptees without severe institutional deprivation.
- Research type
- Neuroimaging cohort
- Source reviewed
- Abstract
- Peer reviewed
- Yes
- Age group
- Young adults
Study context and review
Age group as recorded: Young adults
Adoption context: Intercountry adoption; institutional care
Programme: English and Romanian Adoptees Study
Institutional context: No relationship identified in the material checked
No adoption-sector organisational relationship identified in the bibliographic material screened. This is not confirmation of institutional independence; affiliations, funding and conflicts were not comprehensively audited.
Bibliographic screening. Bibliographic relationships are not a bias or safety rating.
Topics: brain development, institutional deprivation, neurodevelopment, UK research
Review scope: Source checked: Abstract. This does not imply full-text or independent human verification.
Country as recorded: UK; Romania
- Funding
- Not yet checked for this entry
- Commissioner
- Not yet checked for this entry
- Funder role
- Not yet checked for this entry
- Declared conflicts
- Not yet checked for this entry
- Recruitment
- Not yet checked for this entry
- Adoptee involvement
- Not yet checked for this entry
Entry: study_7c1c5ad882bb51ec