Research entry

Estimating effects of parents' cognitive and non-cognitive skills on offspring education using polygenic scores

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Estimating effects of parents' cognitive and non-cognitive skills on offspring education using polygenic scores

Demange PA, Hottenga JJ, Abdellaoui A, Eilertsen EM, Malanchini M, Domingue BW, Armstrong-Carter E, de Zeeuw EL, Rimfeld K, Boomsma DI, van Bergen E, Breen G, Nivard MG, Cheesman R · Nature communications

Researchers compared sibling, adoption and parent–offspring genetic designs across UK and Dutch cohorts to examine education. The adoption analysis included 6,407 adoptees. Across designs, indirect parental genetic associations accounted for part of the overall education association, but estimates were lower in the adoption design. The authors considered prenatal effects and population structure as possible explanations for differences.

Limitations: Results combine cohorts and designs and should not be treated as adoptee-only effects. Polygenic associations do not determine individual ability or educational outcomes. Unknown adoption circumstances and genetic confounding complicate interpretation. The UK Biobank component overlaps with other database papers.

Research type
Secondary cohort analysis
Source reviewed
Abstract
Peer reviewed
Yes
Age group
Adults / Older adults
Study context and review

Age group as recorded: Adults / older adults

Adoption context: Mixed adoption pathways

Programme: UK Biobank

Institutional context: No relationship identified in the material checked

No adoption-sector organisational relationship identified from metadata reviewed. Funding and conflicts were not comprehensively audited; this is not confirmation of institutional independence.

Bibliographic screening. Bibliographic relationships are not a bias or safety rating.

Topics: education, genetics, research methodology

Review scope: Source checked: Abstract. This does not imply full-text or independent human verification.

Country as recorded: United Kingdom / Netherlands

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Funder role
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Declared conflicts
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Recruitment
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Adoptee involvement
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Entry: study_1899d2810d6254b0

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